A Human Histidyl-tRNA Synthetase Splice Variant Therapeutic Targets NRP2 to Resolve Lung Inflammation and Fibrosis

Nangle LA, Xu Z, Siefker D, Burkart C, Chong YE, Zhai L, Geng Y, Polizzi C, Guy L, Eide L, Tong Y, Klopp-Savino S, Ferrer M, Rauch K, Wang A, Hamel K, Crampton S, Paz S, Chiang K, Do M, Burman L, Lee D, Zhang M, Ogilvie K, King D, Adams RA, Schimmel P.
Science Translational Medicine (2025)