Career Opportunities

aTyr offers a competitive compensation package with stock options. We also offer a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) plan matching contribution. For consideration, please submit your resume and cover letter referencing one of our open position numbers to jobs@atyrpharma.com.

aTyr is an equal opportunity employer and makes employment decisions without regard to age, race, ancestry, color, sex, national origin, sexual orientation, gender, gender identity, gender expression, religious creed, disability, medical condition, genetic information, marital status, veteran status or participation in the uniformed military services of the United States, including the National Guard.

Open Positions:

Financial Reporting and SOX Compliance Staff Accountant

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

Primary Responsibilities:

  • Manage updates to the Company’s SOX compliance documentation including Control Matrices, Process Narratives, and monitoring compliance through interviews and document review
  • Coordinate with external SOX service provider walkthroughs, testing and process reviews
  • Assist with flowcharting SOX processes
  • Provide SOX training to process owners in their preparation of controls documentation and testing of SOX controls
  • Recommend best practices to the process owners regarding remediation of findings
  • Develop strong relationships with internal business partners and act as a subject matter expert in the design and implementation of controls
  • Review test findings and facilitate remediation of control gaps and escalate possible critical issues to the senior management of the company
  • Assist in preparation of SEC filings, including but not limited to: 10-Q, 10-K, proxy statement, 8-K and Section 16 filings
  • Generate monthly financial statement reports
  • Assist in preparation of the budget templates and roll-up’s
  • Assist accounting for all equity plan activity, including stock-based compensation expense
  • Participate in ad-hoc projects

Qualifications:

  • Must be a CPA or CPA candidate
  • Possess 2-3 years of experience with a public Biotech company
  • Experience with budget and forecast templates
  • Possess technical expertise related to Sarbanes-Oxley requirements, COSO Framework, Internal Audit and Internal Controls
  • Recent experience with SOX controls documentation and testing
  • Experience in end-to-end project management, controls evaluation, and cross-functional collaboration
  • Strong organizational, analytical, and problem-solving skills 
  • Ability to multi-task and prioritize to meet deadlines
  • Excellent communication skills, both written and verbal 
  • Self-motivated, proactive and detail oriented
  • Proficient with Microsoft Office applications 

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job #188AP to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

Vice President, Finance

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

The VP of Finance will be responsible for leading and coordinating the overall day-to-day finance, accounting, internal controls and budgeting activities of the organization to support the needs and requirements of the company. This position reports directly to the CFO.

Key Responsibilities:

  • Oversee all general accounting functions including the monthly financial close processes, technical accounting, internal controls, financial systems, stock administration, and taxation. 
  • Oversees all reporting financial reporting and cash management. Performs detailed review and analysis of the financials, inclusive of foreign subsidiary and other entities as required.
  • Plans, directs and coordinates all SEC filings and ensures disclosures are complete and accurate.
  • Manage and monitor annual budgets, forecasts, month-end reporting of actual results, including variance analysis to forecast and budget, and cash forecasts 
  • Work with the senior executives to understand the business to be able to develop financial models to support the strategic initiatives of the company. 
  • Prepare and develop materials for Audit Committee and Board Meetings. 
  • Responsible for researching and implementing new developments in GAAP and statutory accounting pronouncements that impact the business. 
  • Provide support to the department heads, including the clinical, manufacturing and research teams, to create transparency around key financial parameters and assumptions, including spending controls/limits and expense accruals. 
  • Drive robust financial analytics, coupled with business insights on potential new clinical programs. 
  • Partner closely with third parties to manage annual and quarterly audits, filings, taxes, and corporate accounting activities. 
  • Manage the internal SOX process from design to execution phase and ensure key controls are in place and operating effectively. 
  • Evaluate, select, implement and maintain ERP and other accounting systems. 
  • Oversee the company’s equity programs, capitalization table, options ledger and maintenance of stock/option related matters. Prepare stock compensation calculations and related accounting. 
  • Responsible for complete and accurate tax compliance and tax accounting in conjunction with external tax advisors.
  • Reviews agreements and operational contracts to ensure proper accounting and reporting.
  • Maintains adequate property and liability insurance by reviewing level of risk with insurance brokers. Recommends any changes necessary to maintain adequate protection while managing costs.
  • Effectively hire and manage the accounting/finance team including supervising direct reports by providing regular feedback, setting annual goals, completing regular performance feedback evaluations. 
  • Ensure all accounting policies and procedures are refined and in place to provide assurance that company assets are protected. 

Qualifications:

  • Bachelor’s degree in Accounting, Finance or equivalent. 
  • CPA required with deep knowledge of US GAAP, SOX, and SEC regulations. 
  • 15+ years of progressively responsible accounting or financial reporting experience. 
  • Big 4 public accounting experience preferred. 
  • Public Biotechnology/Pharmaceutical industry experience required.
  • Experience operating in a Sarbanes Oxley control environment. 
  • Must have strong Microsoft Excel skills and experience evaluating and implementing and managing ERP, purchasing and other accounting systems. 
  • Experience managing teams. 
  • Excellent interpersonal and communication skills. 

Scientist/Sr. Scientist, Nonclinical/Translational Research

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

Primary Responsibilities:

The Scientist / Senior Scientist – Nonclinical / Translational Research will support the early phase development of novel therapies for oncology and inflammatory diseases. The successful candidate will function as a nonclinical scientist providing scientific expertise in support of programs from discovery through both early and late phases of clinical development. Core responsibilities will include oversight of IND-enabling toxicology studies at external CROs as study monitor, execution of studies within program timelines, and toxicology data interpretation and reporting. In addition, the candidate will be involved in advancing our exploratory molecules in preclinical efficacy studies, i.e. conceptualize and run clinically relevant in vivo models, critically review emerging data and construct hypotheses based on these data.

Qualifications:

  • The role requires the ability to collaborate with colleagues in a cross-functional, fastpaced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines. The ideal candidate will have:
  • Ph.D. in biology, pharmacology, or related discipline
  • 2 – 5 years of relevant industry experience, including research and development of biologic therapeutics
  • Proven track record in conducting and/or supervising nonclinical or translational research
  • Knowledge of current regulatory requirements and FDA guidance for the development of biologics
  • Experience with pharmacokinetic modeling of biologics and appropriate software tools (e.g., Phoenix WinNonlin) is a plus
  • Strong organizational and project management skills and the ability to work with minimal supervision and a high level of initiative.
  • Excellent verbal and written communication skills

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job #190CB to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

Scientist, In Vitro Biology (BioAnalytical)

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

Primary Responsibilities:

aTyr Pharma is seeking an enthusiastic and outstanding Scientist to join the In Vitro Biology team. This Scientist will effectively manage the development of clinical assays to support multiple drug candidates. Examples of these assays include pharmacokinetic, anti-drug antibody and neutralizing antibody assays from conception to external validation. This Scientist will also participate in discovery related projects to further advance our novel class of drug targets.

Qualifications:

This role requires the ability to collaborate with colleagues in a cross-functional, intensely fast-paced team environment. The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines.

The ideal candidate:

  • PhD degree in biological sciences or a related discipline (0-3 years’ experience)
  • Experienced with clinical assay development through qualification/validation
  • Skilled in managing external CROs to advance projects on schedule and capable of troubleshooting results
  • Demonstrated expertise in the culture of mammalian cells and performing cell-based assays
  • Must be able to provide data in high-quality presentation formats (graphs, figures, tables, etc.)
  • Concisely document experiments and present results at internal meetings
  • Actively participate in the writing of technical reports and analytical method protocols
  • Should be able to work with minimal supervision and a high level of initiative
  • Strong analytical background, problem solving ability, verbal and written communication skills

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job 187RA to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

Associate/Sr. Associate Corporate Development

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

Primary Responsibilities:

  • Generation and maintenance of aTyr product modeling (risk adjusted discounted cash flow valuation models). Development of transaction models to evaluate deal term NPV. Building pro-forma P&L for aTyr business
  • Managing business development tracking activities, including organizing weekly meetings and owning partnering database
  • Screening of potential partners. Maintaining current understanding of each potential partner’s current business drivers, partnering objectives, technical capabilities, financial strength, and product portfolio
  • Competitive / therapeutic landscape analysis: therapeutic pipelines, marketed products (standard of care) analysis, epidemiology analysis, deal comps, etc
  • Material preparation and negotiation support in partnering meetings
  • Sourcing information from cross functional internal teams, including senior management
  • Support of contracting and negotiation of strategic corporate transactions
  • Support corporate financing initiatives

Skills

  • Demonstrated ability to understand and generate financial models using MS excel, including forecasting, product P&L modeling, probability adjusted NPVs, etc
  • Working knowledge of pharmaceutical development and regulatory processes
  • Strong MS Powerpoint and presentation capabilities
  • Scientifically fluent
  • Understanding of how to source industry information (scientific advances, relevant deals, etc) including using competitive intelligence databases
  • Strong time management and organization skills

Attributes

  • Clear, concise, poised communication
  • Detail oriented, proactive, ability to manage cross-functional groups and execute plans on rigid timelines
  • Small company mindset – works well and adapts quickly in a fast-paced, fast-changing, high-growth environment
  • Team player
  • Ability to manage sensitive information in confidence and with discretion
  • Ability to prioritize multiple high priority tasks effectively

Qualifications:

  • 5 years relevant industry experience (Biotech, pharma, healthcare consulting, healthcare banking / research, healthcare investing) or MBA, plus 3 years
  • Scientific or finance undergraduate degree required

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job 185PV to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

Clinical Trial Manager

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

Job Description

The Clinical Trial Manager (CTM) in collaboration with the Associate Director, Clinical Operations (AD CO) or Clinic Project Manager (CPM), contributes to the operational execution of clinical studies to ensure delivery on time, within budget, and of high quality in compliance with ICH/GCP, Regulatory Authorities’ regulations/guidelines, and applicable SOPs. The CTM is responsible for oversight of site activities as well as for all aspects of monitoring team performance such as patient recruitment, quality of the clinical data, completeness of the TMF and compliance with SOPs and GCP.

This position maybe remote or a hybrid of remote/in office, depending on where the successful candidate is located.

Role Purpose

  • Key support role to the CPM; accountable for oversight of site activities as well as monitoring team performance.
  • Oversees components of clinical trials and ensures that they are executed to specified quality standards, meets project timelines and within budget.
  • Provides GCP expertise and brings to bear best practices in areas of oversight, including: monitoring, TMF content, clinical trial supply, and sample collection

Primary Responsibilities:

  • Thoroughly understands clinical trial protocols and site specifications and manages the oversight of the data delivery process in clinical trials ensuring consistency with protocols, including participation in data review/reconciliation efforts.
  • Oversees monitor performance including development of the study monitoring plan and oversight of activities at the study level. Responsible for site monitoring report review as well as adherence to the study monitoring plan and applicable SOPs and processes. Proactively communicate issues to the CPM.
  • Responsible for managing the creation, maintenance and close out of Trial Master File (TMF) activities. Contributes to TMF quality plan development. Performs QC of Trial Master Files.
  • Responsible for oversight of site activities. Manages aspects of the relationship with trial sites; works with CPM or other Clinical Operations senior staff to resolve issues or problems with the sites
  • Ensures patient enrollment activities are within protocol guidelines.
  • Contribute to the development of and ensures adherence to the clinical trial study plans (quality, vendor management, data management, site monitoring, TMF quality control, and study communication plans)
  • Supports the CPM in the set-up, conduct, and close out of clinical study activities, including management of vendors.
  • Tracks the clinical trial budget by reviewing invoices and identifying changes in scope.
  • Provides study level information to enable accurate and efficient supply of clinical product to the sites. Proactively identifies and communicates potential risks/challenges.
  • Reviews and provides input to clinical protocols for feasibility of clinical trials delivery; looks for short and long-term potential obstacles or opportunities for accelerating delivery of a clinical study
  • Tracks elements of the clinical trial project timelines on a day to day basis, proactively alerting PM and/or senior Clinical Operations staff to risks / challenges
  • Ensures accurate and comprehensive completion of documents needed by Regulatory Affairs or delegate; makes sure that completed documents are handed over to RA within the requested timeframes and ahead of submission deadlines
  • Interfaces with other functional groups to coordinate relevant and timely exchange of information / materials to support clinical trials delivery within the drug development process. Supports CPM in preparation of study reporting.
  • Supports CPM in ensuring that patient enrollment activities are conducted in a timely manner.
  • Provides study level information to ensure timely database lock can occur.
  • Actively participates in the development of department initiatives, may act as lead on the development/definition of certain SOPs and processes under the leadership of more senior Clinical Operations staff; provides suggestions on department initiatives and goals that will support and enhance the vision and mission of Clinical Operations

Qualifications:

  • Demonstrates advanced knowledge of and appropriate experience of relevant software packages (e.g. Microsoft Project, Word, Excel, Power Point) and programs.
  • Demonstrates thorough knowledge and understanding of key regulatory authorities, ICH Guidelines, and GCPs governing the conduct of routine clinical trials.
  • Learns, interprets, and explains protocol requirements to others.
  • Manages components of clinical trials independently with limited general guidance from senior staff.
  • Strong communication, verbal, written and presentation skills.
  • Bachelor’s degree in relevant field or equivalent experience
  • 4+ years experience in Clinical Trial Operations or Research
  • Ability and willingness to travel as needed

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job 176RA to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

Executive Assistant

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

This position requires a dynamic and self-motivated candidate to provide administrative support to C-Level Executives and associated executives, effectively partnering with the leadership team. There will be frequent interactions with employees throughout the organization, including board members along with frequent access to highly confidential information and files. The role will work closely and collaboratively with other Executive Assistants to provide seamless and cohesive coverage for the executive team as a whole while coordinating complex activities and working independently to handle a wide range of administrative and executive support related tasks with little or no supervision.

Primary Responsibilities:

  • Provide administrative and executive support to Senior Leadership supporting Finance, Investor Relations, Purchasing, Facilities and Information Technology activities.
  • Serve as first-point-of contact for supported Executives, autonomously prioritizing and making decisions regarding the Executive’s time and resources.
  • Effectively manage executive’s calendar, contacts, and internal and external communication related to meetings, conference calls, invitations, event planning, board meetings, etc.
  • Participate as part of a team in planning, coordinating and executing conferences and events such as: healthcare conferences, analyst, investor or key opinion leader events, non-deal investor roadshows.
  • Communicate executive’s instructions or desires to various individuals and/or departments and furnishes and obtains information from other executives.
  • Assist in the preparation of executive, advisory and external meetings, to include preparation of materials and agenda, capturing meeting minutes, follow through on action items, etc.
  • Coordinate high volume of travel, domestic and international, associated with complex itineraries and meetings. This includes transportation and accommodations, dining, confirming agendas, locations, etc. with participants, preparation of itineraries and identification of cost-efficient travel options, while pro-actively troubleshooting and addressing travel conflicts and issues.
  • Prepare special reports, gathering, and summarizing data.
  • Prepare complex correspondence, reports, spreadsheets and presentations.
  • Independently manage and own special projects, some that may require discretion, confidentiality and sensitivity.
  • Complete timely, accurate and compliant, expense reporting and credit card reconciliation.
  • Participate in, and sometimes lead, process improvement, often establishing processes to accomplish objectives.
  • Act as backup to purchasing and investor relations departments.
  • General office administrative functions as necessary.

Qualifications:

a

  • Associates or Bachelor’s degree with at least 7 years of experience supporting senior executives, at a public biotech company.
  • Experience planning large meetings.
  • Strong proficiency in Google and Microsoft Office including Outlook, PowerPoint, Word and Excel, and Cloud based storage platforms.
  • Ability to exercise sound judgment, use discretion and manage sensitive and confidential information.
  • Demonstrated ability to be pro-active, anticipate issues and effectively problem-solve.
  • Sense of humor

Further Recruiting Information

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume referencing job #177BVA to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

Senior Research Associate, Protein Production

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel immunological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever. An excellent opportunity to become a central member of a supportive and tight-knit team is currently available at aTyr.

Position Summary

We are currently seeking a Senior Research Associate to join the Process Sciences team as we focus on the development of novel medicines derived from our research into new biological pathways. The successful candidate will play an important role in the discovery and development of new drug candidates through the generation of high quality proteins for research use and support of manufacturing process development for clinical candidates.   Primary laboratory responsibilities include upstream protein production with mammalian cell culture processes, DNA production and purification, some cloning work, and related inventory management. Dependent upon experience and interest, there are growth opportunities to work within other functional groups.

Qualifications

The role requires the ability to collaborate with colleagues in a cross-functional, fast-paced team environment. The successful candidate will be self-motivated, meticulous, organized, and flexible, with the ability to handle rapidly changing objectives and timelines. Experience in an industrial lab focused on protein therapeutics discovery/development is also desired.

The ideal candidate will have:

  • BS with 5+ years of biopharmaceutical industry experience or equivalent
  • Experience in development and execution of mammalian cell culture processes for protein production with proven aseptic technique
  • Experience in harvest, clarification, and recovery processes
  • Molecular biology experience with cloning and DNA production experience is a plus
  • Organized and able to plan and execute multiple activities in parallel using efficient time management
  • High level of motivation and initiative with ability to quickly identify issues, troubleshoot, and implement changes as needed
  • Work well independently as part of a dynamic team and collaborate with cross-functional groups
  • Excellent written and verbal communication skills

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

Associate Director, Clinical Operations

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

The Associate Director, Clinical Operations will oversee global clinical trials.

This key role will manage, plan, and execute clinical trials, including creating and managing study timelines, budgets, and study management plans. Additionally, s/he will provide guidance and shared learning with and across teams throughout planning and implementation, as well as ensure clinical operational and development deliverables and timelines are met.

This position maybe remote or a hybrid of remote/in office, depending on where the successful candidate is located.

Primary Responsibilities:

    Manage and lead a team in clinical operations

    Manage and execute clinical programs, including study management, budget and timeline creation

    Lead across functional study teams, and understand the intricacies among the different groups

    Participate in the development of protocols, IBs, CSRs and other clinical documents, ensuring they are completed within study timelines

    Participate in preparation of regulatory filings (e.g. IND, pre-IND, orphan applications etc.) as needed

    Partner with CMC/clinical supplies to provide drug supply assumptions and contribute to design and packaging of supplies for clinical trials

    Manage all aspects of study progress from planning to close-out to assure adherence to intended timelines and achievement of study goals while ensuring quality in accordance with FDA, EMEA, GCP, and ICH guidelines

    Ability to build strong KOL and Principal Investigator relationships

    Liaise with clinical site staff and Investigators as appropriate to ensure optimal Sponsor-site relationships

    May attend and/or participate in Qualification, Initiation and Monitoring site visits

    Lead, plan, and execute clinical Investigator meetings, study meetings, and vendor meetings as needed

    Lead the evaluation, selection and management of Contract Research Organizations (CROs) and other external vendors to ensure successful clinical trial implementation and execution

    Author informed consent forms (ICFs), study management plans and other clinical documents as necessary.

    Provide study specific training as needed

    Develop and ensure execution of activities outlined in various study plans (data management, safety management, and study communication plans)

    Assist in authoring, reviewing and revising of SOPs

    Assist in training of new staff and consultants

    Attend clinical, scientific and industry conferences as needed 

Qualifications:

    Bachelor’s degree required.

    Minimum of 8+ years in clinical operations in the pharmaceutical/biotech industry (5+ years of study management)

    Experience managing clinical trials, budgets, and timelines

    Experience monitoring and/or overseeing clinical studies and conducting PSVs, SIVs, IMVs, and COVs

    Experience managing CROs (or similar), multiple vendors, and complex protocols

    Experience with protocol, ICF, and CSR development

    Experience in global clinical trial management

    Ability to communicate effectively with the team in this remote position.

    Ability and willingness to travel as needed

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job #181LC to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

IT Support Analyst | Systems Administrator

About Us

aTyr Pharma is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways. aTyr’s research and development efforts are concentrated on a newly discovered area of biology, the extracellular functionality and signaling pathways of tRNA synthetases. aTyr has built a global intellectual property estate directed to a potential pipeline of protein compositions derived from 20 tRNA synthetase genes and their extracellular targets. aTyr’s primary focus is ATYR1923, a clinical-stage product candidate which binds to the neuropilin-2 receptor and is designed to down-regulate immune engagement in inflammatory lung diseases. aTyr is publicly traded on Nasdaq under the symbol “LIFE”. For more information, please visit http://www.atyrpharma.com.

Overview

Patients and their challenges provide tremendous drive and meaning to what we do at aTyr. We seek a talented and successful individual that deeply desires to participate in our process to make medicines that change a patient’s life forever.

aTyr Pharma, Inc has a full-time opportunity for a IT Support Analyst to monitor, troubleshoot, implement, and support technical systems and operations, and provide end user support to an expanding and diverse user base. This growing position is part of our overall effort to provide the highest quality service in support of the organization’s operations.

This key team member will show proven communication, analytical and problem-solving skills to help identify, communicate and assist in resolving end-user system issues, and will work closely with Senior members of the team to perform some System Administrator duties.

Our IT department ensures adherence to standards for identity and access profiles across systems such as Active Directory, and Google Workspace , as well as other specialized applications such as Graphpad Prism, Flowjo, WinNonlin and many others. The successful candidate will be part of a tight team providing experience and exposure to Enterprise class storage and virtualization technologies, and will report directly to the Lead System Administrator.

Primary Responsibilities:

  • Providing first-tier support for a diverse Desktop | Mobile deployment environment.
  • Onboarding new hires, responding to basic network and software problems and providing desktop support with the use of a Ticketing system and Naverisk Automation.
  • Assisting with installation and monitoring of productivity applications, multiple scientific applications and instrument systems.
  • Administering users in Active Directory/DUO and Google Workspace/GCPW.
  • Opportunities to participate in the design, planning, implementation and monitoring the health of core Enterprise systems virtual servers and third party applications, and exposure to on-premise & cloud based Virtualization and other Networking Projects.
  • Participating in the planning and upgrading of existing systems and assisting in developing strategies for improvement.
  • Assisting in preparing detailed documentation of systems, services, applications, security, and controls.

Qualifications:

  • Have a 3 year degree in a related field of study or equivalent experience.
  • Have at least 3 years verifiable experience working as a Desktop support role or relevant IT experience with equivalent responsibilities.
  • Have familiarity with ticketing systems and the associated process of opening, responding, updating and closing tickets.
  • Have a strong knowledge of Windows desktop & mobile management, end-user support, troubleshooting and new hire Deployments.
  • Have a basic proficiency with networking, and understand concepts such as VPN, DHCP, DNS, IPv4, IP Subnets, along with routing, switching, and firewalls
  • Have strong proficiency with modern Windows operating systems.
  • Have experience with Active Directory
  • Have experience with Mac computers.
  • Have a working knowledge of Google Enterprise Workspace/Gmail.
  • Have a strong knowledge of Microsoft Productivity software applications.

Personal Growth & Aptitude:

  • A strong interest in Cloud Computing and internet technologies.
  • Have effective communication skills, both written and orally.
  • Good analytical and problem-solving skills, strong desire and ability to troubleshoot problems.
  • Technology focused on client support, systems administration, network administration or related.
  • Demonstrated ability and desire to educate and communicate effectively with diverse users and a wide range of computer and analytical skills.
  • Professional, quick to respond and solutions-based customer service approach.
  • Demonstration of a naturally strong customer focus and ability to work under pressure independently and with other team members.
  • Ability to work onsite 3 days a week.
  • This position may require occasional availability on nights and weekends, so applicants must be flexible during projects/ implementations.

Further Recruiting Information

For additional information about aTyr Pharma, please visit our website at www.atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

In addition to a competitive compensation package with stock options and an Employee Stock Purchase Plan, aTyr Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, life, disability and a 401(k) matching contribution.

For consideration, please submit your resume and cover letter referencing job #193JK to jobs@atyrpharma.com. aTyr Pharma, Inc. is an EEO employer.

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