Danielle Campbell has served as our Vice President, Human Resources since December 2021. Prior to joining aTyr, Ms. Campbell worked at Poseida Therapeutics, Inc., from 2016-2018 in roles related to human resources and facilities management. From 2019-2021, she was Senior Director, Facilities Operations, where she directed all facility operations including site development, maintenance, planning and environmental health and safety. From 2016-2018, she held roles in human resources at Poseida, including Director, Human Resources from 2018-2019 and Senior Manager, Human Resources from 2016-2018, where she managed daily human resources functions to support rapid growth, development and retention of team members. Prior to joining Poseida, Ms. Campbell was Human Resources Manager for aTyr Pharma, Inc., from 2015-2016, where she managed and supported daily human resources functions. Ms. Campbell began her career in human resources with earlier positions including Manager, Human Resources for Celladon Corporation from 2014-2015 and Manager, Human Resources & Equity Plans for Cytori Therapeutics, Inc. Ms. Campbell received a B.A. in Criminology, Law and Society from the University of California, Irvine School of Social Ecology.

Lisa Carey has served as our Vice President, Clinical Operations since May 2023. Ms. Carey has
over 30 years of clinical operations experience. From June 2015 to December 2023, she served as
our Sr. Director, Clinical Operations, overseeing the company’s clinical programs, including
efzofitimod. Prior to joining aTyr, from 2006 to 2015, Ms. Carey worked at Vertex Pharmaceuticals as
a Clinical Operations Consultant in the Global Trial Activation Group, where she facilitated global
Phase 3 trials for Kalydeco® for the treatment of cystic fibrosis, Incivek® for hepatitis C and
lumacaftor for the treatment of cystic fibrosis. From 1997 to 2003, Ms. Carey was as an Associate
Director, Global Study Management, Experimental Medicine in the areas of oncology and infectious
disease at the Genetics Institute/Wyeth Pharmaceuticals, and from 1995 to 1997, she served as a
Project Manager in asthma at Muro Pharmaceutical, Inc. Prior to entering into clinical operations
research, Ms. Carey was a critical care nurse. Ms. Carey has a B.S. in Nursing from Saint Joseph’s
College.

Sanjay S. Shukla, M.D., M.S., has served as our President and Chief Executive Officer and as a director since November 2017. Dr. Shukla served as our Chief Medical Officer from March 2016 to November 2017. From April 2015 to March 2016, Dr. Shukla worked in an advisory capacity for a number of companies, including as a consultant to aTyr from January 2016 to March 2016. Prior to that, from October 2012 to April 2015, Dr. Shukla served as Vice President and Global Head of Integrated Medical Services for Novartis, a biopharmaceutical company, where he led global medical affairs operations, with oversight for all pharma general medicines therapies, both inline and in development. Dr. Shukla served as Chief Executive Officer of RXMD, a clinical development consultancy that assisted in advancing proof of concept for early stage drug candidates, from April 2009 to September 2012. Prior to that, Dr. Shukla served in a variety of clinical development, data analytics and drug safety roles at Vifor Pharma, a biopharmaceutical company, and Aspreva Pharmaceuticals (acquired by Vifor Pharma). Dr. Shukla received his M.D. from Howard University College of Medicine and his Bachelors of Science in Microbiology and Master of Science in Epidemiology and Biostatistics from the University of Maryland.

Brandon Yaras has served as our Chief Financial Officer since October 2026. Mr. Yaras served as our Vice President, Finance from May 2022 to October 2026. Mr. Yaras has nearly 20 years of corporate finance and accounting experience, having overseen internal and external SEC reporting, forecasting and valuation, SOX compliance, payroll and equity administration and accounts payable. Prior to joining aTyr, from 2014 to 2022, he served as Director of Finance and Accounting for Arrowhead Pharmaceuticals, Inc., where he oversaw similar finance and accounting operations as well as procurement. Prior to that, he was Manager of Financial Planning and Analysis for Tutor Perini Corporation from 2009 to 2014, and he began his career in the assurance practice at Deloitte & Touche LLP, most recently serving as an Audit Senior. Mr. Yaras holds a B.A. in business economics with a minor in accounting from the University of California, Los Angeles and is a Certified Public Accountant.

Leslie Nangle, Ph.D., has served as our Vice President, Research since January 2021. Dr. Nangle has served in scientific research roles at aTyr since joining the company in 2007, including most recently as Sr. Director and Head of Research. Dr. Nangle has over 20 years of experience in research dedicated to extracellular tRNA synthetases. Throughout her tenure at aTyr, she has co-developed and implemented the company’s discovery platform to generate an intellectual property estate of over 300 potential therapeutically relevant proteins and has overseen research leading to the discovery of a splice variant of histidyl-tRNA synthetase that has been shown to modulate the immune system, providing the basis of aTyr’s lead program, efzofitimod. Prior to joining aTyr, Dr. Nangle received a Ph.D. in Macromolecular Cellular Structure and Chemistry from The Scripps Research Institute in La Jolla, CA, studying the emerging linkage between mutations in tRNA synthetases and inherited neuropathies under the mentorship of Dr. Paul Schimmel, who co-founded aTyr in 2005. Dr. Nangle received a bachelor of science in biology from the University of California at Santa Barbara. She is co-author or co-inventor of over 75 publications and issued or pending U.S. patents.